Applications of Biochemistry Essay

Blood is one of the most important fluids in the valet de chambre body. It helps carry nutrients such as oxygen to the cells in the body and transports come out wastes like deoxycytidine monophosphate dioxide and former(a) metabolites from these cells. Since blood is the medium through with(predicate) which the polar organs and tissues in our body communicates, keeping a close gist on the constituents of a blood prove would provide a serious indication of the functioning of the human body.Blood gas tests argon say for patients who might have symptoms of pH imbalance, extreme levels of oxygen/ carbon dioxide, or in narrate to evaluate the functioning of organs such as the kidneys and the presence of disorders such as diabetes. The latter tests are measured through the digest of electrolytes and metabolites in the blood. Patients who are on a ventilator in a hospital may have their treatment procedures also monitored development a blood gas analysis test.In the Core lab o f University Hospital in London, Ontario, the hoarded wealth Premiere 3000 Blood Gas analyser is used in order to perform tests on patients. There are two analyzers present in this laboratory. Both machines brush aside run tests for levels of pH, incomplete pressure of carbon dioxide, partial pressure of oxygen, Na+, K+, Ca++, and hematocrit (Hct). One of the machines however, is also capable of running glucose and lactate tests as well.One other(a) final blood constituent that is also potvass in this analyzer is for carboxyhemoglobin. If a ingest is to be tested for carboxyhemoglobin, the sample must be injected from the syringe into the hoarded wealth cuvette. The cuvette is then inserted into another analyzer in order to test carboxyhemoglobin levels. The samples collected for blood gas analysis tests can be arterial, venous, or capillary blood.Reference Range determine of measurements in the normal range using the Gem Premiere 3000 (UCSF health check Center, 2011). either samples are delivered to the laboratory in syringes or capillaries from the bedside of the patient in the hospital. A sample that arrives from the Operation Room can only be stored for and has to be analyzed within 15-20 minutes. Samples that are delivered to the laboratory on starter can be stored for one hour while all other samples must be analyzed within half an hour. Unlike other samples that are analyzed in the lab, these samples are not archived after analysis. e precise(prenominal) samples must also be warmed between the hands forwards being analyzed in order to mix the contents thoroughly. All syringes with samples contain a coating of heparin sulfate in order to avoid the clotting of blood samples. Once the source of blood sample (arterial, venous, capillary) has been selected on the display try of the analyzer, the sample is checked for clots. This is done by testing a drop or two onto a netting pad. The barcode on the sample syringe is then scanned in order to prove the patient ID and store the results.A message then bug outs on the screen of the analyzer that reads Present sample now. The tip of the syringe can then be inserted at an angle, into the needle that protrudes from the Analyzer. The results will then appear on the screen and be relieve on the patients profile according to their ID that was scanned. The maintenance conducted on the Gem Premiere 3000 is very minimal. The Gem Premiere 3000 contains a cartridge that has electrodes with all the normalisation measurements for the machine.The analyzer is checked daily for printer paper. Every week, quality control tests are run in order to ensure the accurate working of the Gem Premiere 3000. The two control tests administered are the Critical Care QC ContrIL9 and the GEM critCheck. The first control tests for the proper analysis of of pH, partial pressure of carbon dioxide, partial pressure of oxygen, Na+, K+ and Ca++, while the snatch control tests for hematocrit low and norm al levels (UCSF Medical Center, 2011).The cartilage with electrodes for calibration measurements expires every three weeks. However, if there is a power cut or an issue with the analyzer, the cartridge must be changed immediately before each other tests are conducted. Once the cartridge has been replaced, it takes half an hour for the cartridge to warm up after the CVP control has been run and before tests can be run again. Once all the tests are run, they are saved on the patients profile and are available for approaching by all physicians and hospital staff throughout the hospital.