PIV Measurement of Fluid Flow Inside a Human Uterus Model for Cryoablation :: essays research papers

PIV MEASUREMENT OF FLUID FLOW INSIDE A HUMAN UTERUS MODEL FOR CRYOABLATIONXiaolong Luo1, Jim S.J. Chen1, Marla Wolfson2, Charles Philips2, Thomas Shaffer21Department of Mechanical Engineering, Temple University2Temple University enlighten of MedicineAbstract A new technique has been proposed that allows cryo cutting out to be achieved on the entire inner surface of the endometrium by circulating very heatless perfluorochemical (perfluorocarbon) peregrine inside the human uterus. To ensure the perfluorocarbon melt down arena inside the uterus during cryoablation, a uterus model was constructed a fluid delivery system including the fluid delivery probe was designed and create to simulate the PFC flow during cryosurgery. With particle image velocimetry (PIV), the fluid flow inside the uterus was investigated at room temperature to display a 2-D building block field velocity contour and vector plot.Keywords PIV, cryoablation, PFC, endometriumI. INTRODUCTIONMenorrhagia is medica lly defined as excessive bleeding at menses, in age or amount. A frequent cause of menorrhagia is uterine fibroid growth. Traditionally, hysterectomy is the master(prenominal) treatment for menorrhagia. Several cryosurgery modes such as localise cryoprobes 1 and balloon ablation 2 have been developed as alternatives to hysterectomy to treat the dysfunction of the endometrium. However, these are localized techniques and sometimes there is still proliferation of the endometrium. A new technique is proposed that allows cryoablation to be achieved on the entire inner surface of the endometrium using a PFC fluid 3. The objective of this project is to develop an efficient treatment method for abnormal uterine bleeding by freezing the endometrium. It has been shown that a temperature of 30 &61616C is required for destroy tissue necrosis 4. The heat steer process during cryoablation was investigated experimentally and numerically (1-D) with good agreement 5, in which a uniform fluid te mperature boundary condition was used in the 1-D bounded difference method to determine the temperature history in the human uteri of eightsome patients. This assumed that the fluid flow inside the uterus is uniform, repeatable and controllable. During the experiments it was appoint that the temperature difference at the inlet and outlet of the insertion probe varied from 10C to 50C. Inconsistent fluid temperatures may be caused by inadequate circulation of PFC liquid, i.e., recirculation within the uterus. The goal of this study is to understand the flow field inside the uterus cavity during cryoablation so that the coveted flow field and uniform temperature field can be obtained, gum olibanum proposing an optimal insertion probe design so that minimum PFC liquid and surgery time is used.